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  1. 首頁 > 生化試劑 > 多肽 > 藥物肽 > Sincalide

Sincalide

    
99%

Sincalide

源葉(MedMol)
S80567 一鍵復(fù)制產(chǎn)品信息
25126-32-3
C49H62N10O16S3
1143.27
辛卡利特;氯縮膽囊素八肽;醋酸辛卡利特;H-ASP-TYR(SO3H)-MET-GLY-TRP-MET-ASP-PHE-NH2;H-ASP-TYR(SO3H)-MET-GLY-TRP-MET-ASP-PHE-NH2 AMMONIUM SALT;CHOLECYSTOKININ [TYR(SO3H)27]-FRAGMENT 26-33 AMIDE;CHOLECYSTOKININ, OCTAPEPTID
貨號 規(guī)格 價格 上海 北京 武漢 南京 購買數(shù)量
S80567-1mg 99% ￥290.00 9 - - -
S80567-5mg 99% ￥790.00 8 - - -
S80567-25mg 99% ￥2500.00 5 - - -
產(chǎn)品介紹 參考文獻(xiàn) 質(zhì)檢證書(COA) 摩爾濃度計算器 相關(guān)產(chǎn)品

產(chǎn)品介紹

Sincalide (Cholecystokinin octapeptide, CCK‐8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. CCK‐8 is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK‐8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. CCK‐8 can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. CCK‐8 is a major bioactive segment of CCK that retains most of the biological activities of CCK

產(chǎn)品描述： Sincalide (Cholecystokinin octapeptide, CCK‐8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. CCK‐8 is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK‐8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. CCK‐8 can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. CCK‐8 is a major bioactive segment of CCK that retains most of the biological activities of CCK
靶點： Cholecystokinin Receptor;Apoptosis;PI3KAkt
體內(nèi)研究： Sincalide (Cholecystokinin octapeptide, CCK‐8) (i.p.; 50 μg/kg/d; for 4 weeks) alleviates fibrosis in the noninfarcted regions and delay the left ventricular remodeling and the progress of heart failure in a MI rat model
參考文獻(xiàn)： 1. Maher KA et al. Kinevac (sincalide for injection)/Squibb Diagnostics. Gastroenterol Nurs. 1991 Oct;14(2):98-100. 2. Ziessman HA. Sincalide: A Review of Clinical Utility, Proper Infusion Methodology, and Alternative Cholecystogogues. J Nucl Med Technol. 2019 Sep;47(3):210-212. 3. Can Wang, et al. Protective effect of cholecystokinin octapeptide on angiotensin II-induced apoptosis in H9c2 cardiomyoblast cells. J Cell Biochem. 2020 Jul;121(7):3560-3569. 4. Can Wang, et al. Cholecystokinin octapeptide reduces myocardial fibrosis and improves cardiac remodeling in post myocardial infarction rats. Int J Biochem Cell Biol. 2020 Aug;125:105793.
溶解性： DMF  :  50  mg/mL  (43.73  mM;  Need  ultrasonic)    H2O  :  0.1  mg/mL  (0.09  mM;  Need  ultrasonic  and  warming)
保存條件： -20℃
配置溶液濃度參考：
1mg 5mg 10mg
1 mM 0.875 ml 4.373 ml 8.747 ml
5 mM 0.175 ml 0.875 ml 1.749 ml
10 mM 0.087 ml 0.437 ml 0.875 ml
50 mM 0.017 ml 0.087 ml 0.175 ml
注意： 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)

質(zhì)檢證書(COA)

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批號：JS298415 貨號：S20001-25g
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摩爾濃度計算器

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