| 貨號(hào) | 規(guī)格 | 價(jià)格 | 上海 | 北京 | 武漢 | 南京 | 購(gòu)買(mǎi)數(shù)量 |
|---|---|---|---|---|---|---|---|
S88712-2mg |
98.5% | ￥510.00 | 5 | - | - | - |
|
S88712-5mg |
98.5% | ￥765.00 | 6 | - | - | - |
|
S88712-10mg |
98.5% | ￥1360.00 | 6 | - | - | - |
|
S88712-25mg |
98.5% | ￥2400.00 | 6 | - | - | - |
|
S88712-50mg |
98.5% | ￥3500.00 | 5 | - | - | - |
|
S88712-100mg |
≥98% | ￥5100.00 | 貨期：2-3天 | - | - | - |
|
GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein
| 產(chǎn)品描述： | GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶點(diǎn)： | MEK5;MEK | ||||||||||||||||||||
| 體外研究： | GW284543 (10 和 20 μM；6 小時(shí)) 處理以劑量依賴性方式抑制 MEK5 并降低 pERK5。 Western Blot Analysis Cell Line: MIA PaCa-2 cells Concentration: 10 and 20 μM Incubation Time: 6 hours Result: Reduced phosphorylation of ERK5, and decreased endogenous MYC protein. | ||||||||||||||||||||
| 參考文獻(xiàn)： | 1. Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7. | ||||||||||||||||||||
| 溶解性： | Soluble in DMSO | ||||||||||||||||||||
| 保存條件： | -20°C | ||||||||||||||||||||
| 配置溶液濃度參考： |
|
||||||||||||||||||||
| 注意： | 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。 |
上海工商
滬公網(wǎng)安備 31011702002021號(hào)
危險(xiǎn)品化學(xué)品經(jīng)營(yíng)許可證（不帶存儲(chǔ)）
營(yíng)業(yè)執(zhí)照(三證合一)
掃一掃關(guān)注上海源葉微信公眾號(hào)
北京