貨號	規(guī)格	價格	上海	北京	武漢	南京
S86567-2mg	≥98%	￥238.00 S86567-2mg ￥238.00 現(xiàn)貨	0 1 貨期：2-3天	1	-	-
S86567-5mg	98.2%	￥330.00 S86567-5mg ￥330.00 現(xiàn)貨	5 5	-	-	-
S86567-10mg	98.2%	￥560.00 S86567-10mg ￥560.00 現(xiàn)貨	1 1	-	-	-
S86567-25mg	98.2%	￥1120.00 S86567-25mg ￥1120.00 現(xiàn)貨	2 2	-	-	-
S86567-50mg	≥98%	￥1615.00 S86567-50mg ￥1615.00 2-3天	0 貨期：2-3天	-	-	-
S86567-100mg	≥98%	￥2720.00 S86567-100mg ￥2720.00 2-3天	0 貨期：2-3天	-	-	-

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產(chǎn)品介紹

PHTPP is a selective ERβ antagonist.

產(chǎn)品描述：

PHTPP is a selective ERβ antagonist.

靶點：

Estrogen Receptor/ERR;Estrogen/progestogen Receptor;EstrogenReceptor/ERR;Estrogen/progestogenReceptor

細(xì)胞實驗：

Cells are plated at a density of 3 to 4×10^5 in 1 mL of medium per well in a 24-well plate for cell viability and cAMP analysis. Cells are cultured in Dulbecco's Modified Eagle Medium with PHTPP (1 μM), or ethanol (0.1%) as the vehicle. The incubator is set to an atmosphere of 5% CO2 in air at 37°C, and cultures are allowed to acclimate for at least 24 h. The culture medium is then aspirated and replaced with serum-free DMEM/F12 containing 0.1 μM androstenedione. The cells are collected for intracellular cAMP and to test cell viability. They are for reference only.

參考文獻(xiàn)：

1.Wang K, Chen Y, Gao S, et al. Norlichexanthone purified from plant endophyte prevents postmenopausal osteoporosis by targeting ERα to inhibit RANKL signaling[J]. Acta Pharmaceutica Sinica B. 2020 2.Compton DR, etal. Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity. J Med Chem. 2004 Nov 18;47(24):5872-93.

溶解性：

Soluble in DMSO

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	2.362 ml	11.812 ml	23.623 ml
5 mM	0.472 ml	2.362 ml	4.725 ml
10 mM	0.236 ml	1.181 ml	2.362 ml
50 mM	0.047 ml	0.236 ml	0.472 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(1篇)

1. [IF=4.285] Li Pan et al."ESR1 mediates estrogen-induced feminization of genetic male Chinese soft-shelled turtle."BIOLOGY OF REPRODUCTION. 2022 May;:

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PHTPP

4-[2-PHENYL-5,7-BIS(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]PHENOL