貨號(hào)	規(guī)格	價(jià)格	上海	北京	武漢	南京
S86078-50mg	99.6%	￥168.00 S86078-50mg ￥168.00 現(xiàn)貨	7 7	-	-	-
S86078-100mg	99.6%	￥320.00 S86078-100mg ￥320.00 現(xiàn)貨	3 3	-	-	-
S86078-500mg	≥98%	￥800.00 S86078-500mg ￥800.00 2-3天	0 貨期：2-3天	-	-	-

產(chǎn)品介紹

Guanethidine sulfate (Guanethidine monosulfate) ia an antihypertensive agents. Guanethidine is also an adrenergic neurone blocking drug, enters noradrenergic nerve terminals by the neuronal amine carrier

產(chǎn)品描述：

靶點(diǎn)：

Norepinephrine

體內(nèi)研究：

Guanethidine (5-40 mg/kg; intraperitoneal injection; daily; for 4-28 days; male Wistar rats) treatment for 28 days by 40 mg/kg results in an incomplete sympathectomy accompanied by a partially irreversible hypersensitivity to noradrenaline, whereas 5 mg/kg does not induce histological or permanent haemodynamic changes

參考文獻(xiàn)：

1. Mitchell JR, et al. Antagonism of the antihypertensive action of guanethidine sulfate by desipramine hydrochloride. JAMA. 1967 Dec 4;202(10):973-6. 2. Nielsen GD. Guanethidine induced sympathectomy in the adult rat. I. Functional effects following subacute administration. Acta Pharmacol Toxicol (Copenh). 1977 Sep;41(3):203-8. 3. Fabiani ME, et al. Inhibition of sympathetic noradrenergic transmission by guanabenz and guanethidine in rat isolated mesenteric artery: involvement of neuronal potassium channels. Pharmacol Res. 1996 Mar;33(3):171-80.

溶解性：

Soluble in H2O

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	3.374 ml	16.87 ml	33.739 ml
5 mM	0.675 ml	3.374 ml	6.748 ml
10 mM	0.337 ml	1.687 ml	3.374 ml
50 mM	0.067 ml	0.337 ml	0.675 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)

質(zhì)檢證書(COA)

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批號(hào)：JS298415 貨號(hào)：S20001-25g
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摩爾濃度計(jì)算器

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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Guanethidine Monosulfate