貨號(hào)	規(guī)格	價(jià)格	上海	北京	武漢	南京
S83235-5mg	≥98%	￥400.00 S83235-5mg ￥400.00 咨詢	0 貨期：咨詢	-	-	-
S83235-10mg	≥98%	￥550.00 S83235-10mg ￥550.00 咨詢	0 貨期：咨詢	-	-	-
S83235-50mg	≥98%	￥1200.00 S83235-50mg ￥1200.00 咨詢	0 貨期：咨詢	-	-	-
S83235-100mg	≥98%	￥1800.00 S83235-100mg ￥1800.00 咨詢	0 貨期：咨詢	-	-	-

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產(chǎn)品介紹

Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents.

產(chǎn)品描述：

Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents.

靶點(diǎn)：

DNA Alkylator/Crosslinker;DNAAlkylator/Crosslinker

體外研究：

Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis

體內(nèi)研究：

Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells

參考文獻(xiàn)：

1. Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23(3):344-8. 2. Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64(3):473-83.

溶解性：

10 mM in DMSO

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	1.309 ml	6.545 ml	13.089 ml
5 mM	0.262 ml	1.309 ml	2.618 ml
10 mM	0.131 ml	0.654 ml	1.309 ml
50 mM	0.026 ml	0.131 ml	0.262 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)

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Miriplatin