| 貨號 | 規(guī)格 | 價格 | 上海 | 北京 | 武漢 | 南京 | 購買數(shù)量 |
|---|---|---|---|---|---|---|---|
S82221-2mg |
99.7% | ￥272.00 | 5 | - | - | - |
|
S82221-5mg |
99.7% | ￥369.00 | 6 | - | - | - |
|
S82221-10mg |
99.7% | ￥663.00 | 6 | - | - | - |
|
S82221-25mg |
99.7% | ￥1530.00 | 7 | - | - | - |
|
S82221-50mg |
99.7% | ￥2400.00 | 5 | - | - | - |
|
S82221-100mg |
≥98% | ￥3500.00 | 貨期：2-3天 | - | - | - |
|
AG126 is a tyrosine kinase inhibitor, can inhibit the phosphorylation of ERK1 and ERK2 at 25-50 μM. AG126 can be used in meiosis, mitosis, and postmitotic research
| 產(chǎn)品描述： | AG126 is a tyrosine kinase inhibitor, can inhibit the phosphorylation of ERK1 and ERK2 at 25-50 μM. AG126 can be used in meiosis, mitosis, and postmitotic research | ||||||||||||||||||||
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| 靶點： | ERK2;ERK;?COX | ||||||||||||||||||||
| 體內(nèi)研究： | AG 126 (intraperitoneal injection; 1-10 mg/kg; 1 h and 6 h after Zymosan treatment) treatment attenuates the degree of multiple organ failure (MOF) associated with Zymosan-induced peritonitis in the rat | ||||||||||||||||||||
| 參考文獻： | 1. Cuzzocrea S, et al. The tyrosine kinase inhibitor tyrphostin AG126 reduces the development of acute and chronic inflammation. Am J Pathol. 2000 Jul;157(1):145-58. 2. Garg TK, et al. Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2. BMC Ophthalmol. 2003 Mar 21;3:5. 3. Dugo L, et al. The tyrosine kinase inhibitor tyrphostin AG 126 reduces the multiple organ failure induced by zymosan in the rat. Intensive Care Med. 2002 Jun;28(6):775-88. 4. Bullard LE, et al. Role for extracellular signal-responsive kinase-1 and -2 in retinal angiogenesis. Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1722-31. | ||||||||||||||||||||
| 溶解性： | DMSO : 100 mg/mL (464.75 mM; Need ultrasonic and warming) | ||||||||||||||||||||
| 保存條件： | -20℃ | ||||||||||||||||||||
| 配置溶液濃度參考： |
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| 注意： | 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。 |
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危險品化學(xué)品經(jīng)營許可證（不帶存儲）
營業(yè)執(zhí)照(三證合一)
北京