貨號	規(guī)格	價格	上海	北京	武漢	南京
S81486-5mg	99.0%	￥200.00 S81486-5mg ￥200.00 現(xiàn)貨	9 9	-	-	-
S81486-10mg	99.0%	￥240.00 S81486-10mg ￥240.00 現(xiàn)貨	7 7	-	-	-
S81486-25mg	99.0%	￥480.00 S81486-25mg ￥480.00 現(xiàn)貨	2 2	-	-	-
S81486-50mg	99.0%	￥850.00 S81486-50mg ￥850.00 現(xiàn)貨	4 4	-	-	-
S81486-100mg	99.0%	￥1600.00 S81486-100mg ￥1600.00 現(xiàn)貨	6 6 6	2	2	2
S81486-1g	99.0%	￥5800.00 S81486-1g ￥5800.00 現(xiàn)貨	1 1	-	-	-

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產(chǎn)品介紹

(-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.

產(chǎn)品描述：

(-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.

靶點：

Human Endogenous Metabolite;EstrogenReceptor/ERR;?Estrogen/progestogenReceptor;?EndogenousMetabolite

體內(nèi)研究：

(-)-(S)-Equol inhibits the tumor growth by 43.2% and 28.4% compared to the control on day 33, suggesting that the compound is not overtly toxic

參考文獻：

1. Setchell KD, et al. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81(5):1072-9. 2. Lu Z, et al. S-equol, a Secondary Metabolite of Natural Anticancer Isoflavone Daidzein, Inhibits Prostate Cancer Growth In Vitro and In Vivo, Though Activating the Akt/FOXO3a Pathway. Curr Cancer Drug Targets. 2016;16(5):455-65. 3. Horiuchi H, et al. S-equol nantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells. J Nutr Sci Vitaminol (Tokyo). 2014;60(4):291-6.

溶解性：

DMSO : 100 mg/mL (412.76 mM; Need ultrasonic and warming)

保存條件：

-20℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	4.128 ml	20.638 ml	41.276 ml
5 mM	0.826 ml	4.128 ml	8.255 ml
10 mM	0.413 ml	2.064 ml	4.128 ml
50 mM	0.083 ml	0.413 ml	0.826 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻(2篇)

2. [IF=5.1] Xiaoying Wang et al."Preparation of Lactobacillus rhamnosus ATCC 7469 microencapsulated-lactulose synbiotic and its effect on equol production."Food & Function.2024 Aug;: 1. [IF=5.396] Cong Lu et al."S-equol, a metabolite of dietary soy isoflavones, alleviates lipopolysaccharide-induced depressive-like behavior in mice by inhibiting neuroinflammation and enhancing synaptic plasticity."Food Funct. 2021 Jul;12(13):5770-5778

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（S）-Equol