| 貨號(hào) | 規(guī)格 | 價(jià)格 | 上海 | 北京 | 武漢 | 南京 | 購(gòu)買(mǎi)數(shù)量 |
|---|---|---|---|---|---|---|---|
S81333-2mg |
99.4% | ￥140.00 | 5 | - | - | - |
|
S81333-5mg |
99.4% | ￥240.00 | 5 | - | - | - |
|
S81333-10mg |
99.4% | ￥450.00 | 6 | - | - | - |
|
S81333-25mg |
99.4% | ￥1080.00 | 6 | - | - | - |
|
XMD17-109 is a novel, specific ERK-5 inhibitor, with an IC50 of 162 nM.
| 產(chǎn)品描述： | XMD17-109 is a novel, specific ERK-5 inhibitor, with an IC50 of 162 nM. | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶點(diǎn)： | ERK5:162 nM (IC50);LRRK2[G2019S]:339 nM (IC50);ERK | ||||||||||||||||||||
| 參考文獻(xiàn)： | 1. Deng X, et al. Structural determinants for ERK5 (MAPK7) and leucine rich repeat kinase 2 activities of benzo[e]pyrimido-[5,4-b]diazepine-6(11H)-ones. Eur J Med Chem. 2013;70:758-67. 2. Elkins, Jonathan M., et al. X-ray Crystal Structure of ERK5 (MAPK7) in Complex with a Specific Inhibitor. Journal of Medicinal Chemistry (2013), 56(11), 4413-4421. 3. Wilhelmsen K, et al. Extracellular signal-regulated kinase 5 promotes acute cellular and systemic inflammation. Sci Signal. 2015 Aug 25;8(391):ra86. | ||||||||||||||||||||
| 溶解性： | DMSO : ≥ 100 mg/mL (156.54 mM) | ||||||||||||||||||||
| 保存條件： | -20℃ | ||||||||||||||||||||
| 配置溶液濃度參考： |
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| 注意： | 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。 |
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