| 貨號(hào) | 規(guī)格 | 價(jià)格 | 上海 | 北京 | 武漢 | 南京 | 購買數(shù)量 |
|---|---|---|---|---|---|---|---|
S81279-5mg |
98.5% | ￥110.00 | >10 | - | - | - |
|
S81279-25mg |
98.5% | ￥360.00 | 9 | - | - | - |
|
ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1, Clk2, Clk3 and Dyrk1A/1B
| 產(chǎn)品描述： | ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1, Clk2, Clk3 and Dyrk1A/1B | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶點(diǎn)： | CLK4:136 nM (IC50);CLK1:1522 nM (IC50);CLK2:1648 nM (IC50);DYRK1B:4420 nM (IC50);CDK3:＞10000 nM (IC50);DYRK1A:＞10000 nM (IC50);DYRK;?CDK | ||||||||||||||||||||
| 體外研究： | ML167 has cell permeability in Caco-2 cells. ML167 contains a furan ring which liable to in vivo metabolism. | ||||||||||||||||||||
| 參考文獻(xiàn)： | 1. Rosenthal AS, et al. An inhibitor of the Cdc2-like kinase 4 (Clk4). | ||||||||||||||||||||
| 溶解性： | soluble in DMSO | ||||||||||||||||||||
| 保存條件： | -20℃ | ||||||||||||||||||||
| 配置溶液濃度參考： |
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| 注意： | 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。 |
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