| 貨號(hào) | 規(guī)格 | 價(jià)格 | 上海 | 北京 | 武漢 | 南京 | 購(gòu)買(mǎi)數(shù)量 |
|---|---|---|---|---|---|---|---|
S81019-5mg |
≥99% | ￥400.00 | 貨期：2-3天 | - | - | - |
|
S81019-10mg |
99.3% | ￥720.00 | 1 | - | - | - |
|
S81019-25mg |
99.3% | ￥1440.00 | 4 | - | - | - |
|
S81019-50mg |
99.3% | ￥2160.00 | 6 | - | - | - |
|
(-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II
| 產(chǎn)品描述： | (-)-Blebbistatin is a selective inhibitor of the ATPase activity of non-muscle myosin II | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 靶點(diǎn)： | IC50: 0.5 to 5 μM (myosin II);ATPase;?Myosin | ||||||||||||||||||||
| 體內(nèi)研究： | Blebbistatin dose-dependently and completely relax both KCl- and carbachol-induced rat detrusor and endothelin-1-induced human bladder contraction. Pre-incubation with 10 μM blebbistatin attenuates carbachol responsiveness by 65% while blocking electrical field stimulation-induced bladder contraction reaching 50% inhibition at 32 Hz | ||||||||||||||||||||
| 參考文獻(xiàn)： | 1. Cristina Lucas‐Lopez, et al. Absolute Stereochemical Assignment and Fluorescence Tuning of the Small Molecule Tool, (–)‐Blebbistatin. 2. Ponsaerts R, et al. The myosin II ATPase inhibitor blebbistatin prevents thrombin-induced inhibition of intercellularcalcium wave propagation in corneal endothelial cells. Invest Ophthalmol Vis Sci. 2008 Nov;49(11):4816-27. | ||||||||||||||||||||
| 溶解性： | DMSO : 10 mg/mL (34.21 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble) | ||||||||||||||||||||
| 保存條件： | -20℃ | ||||||||||||||||||||
| 配置溶液濃度參考： |
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| 注意： | 部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶(hù)參考交流研究之用。 |
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