產(chǎn)品描述: | Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome. |
靶點(diǎn): |
Oxazolidinone;MAO;?Antibacterial;?Antibiotic |
體內(nèi)研究: |
For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema |
參考文獻(xiàn): |
1. Choi S, et al. Activity of Tedizolid Phosphate (TR-701) in Murine Models of Infection with Penicillin-resistant and Penicillin-sensitive Streptococcus pneumoniae. Antimicrob Agents Chemother. 2012 Jun 19. |
溶解性: |
DMSO : 10 mg/mL (27.00 mM; Need ultrasonic) |
保存條件: |
2-8℃ |
配置溶液濃度參考: |
|
1mg |
5mg |
10mg |
1 mM |
2.7 ml |
13.501 ml |
27.002 ml |
5 mM |
0.54 ml |
2.7 ml |
5.4 ml |
10 mM |
0.27 ml |
1.35 ml |
2.7 ml |
50 mM |
0.054 ml |
0.27 ml |
0.54 ml |
|
注意: |
部分產(chǎn)品我司僅能提供部分信息,我司不保證所提供信息的權(quán)威性,僅供客戶參考交流研究之用。 |