貨號(hào)	規(guī)格	價(jià)格	上海	北京	武漢	南京
S80944-5mg	98.2%	￥61.00 S80944-5mg ￥61.00 現(xiàn)貨	97419 >10	-	-	-
S80944-10mg	98.2%	￥95.00 S80944-10mg ￥95.00 現(xiàn)貨	48720 >10	-	-	-
S80944-50mg	98.2%	￥102.00 S80944-50mg ￥102.00 現(xiàn)貨	9759 >10	-	-	-
S80944-250mg	98.2%	￥305.00 S80944-250mg ￥305.00 現(xiàn)貨	1968 >10	-	-	-
S80944-1g	98.2%	￥820.00 S80944-1g ￥820.00 現(xiàn)貨	492 >10	-	-	-

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產(chǎn)品介紹

Azithromycin A is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.

產(chǎn)品描述：

Azithromycin A is an antibiotic derived from erythromycin, binding to the 50S subunit of the bacterial ribosome, and thus inhibits translation of mRNA.

靶點(diǎn)：

Antibacterial;Antibiotic

細(xì)胞實(shí)驗(yàn)：

THP-1 cells (106 cells in 1 mL RPMI medium, without antibiotics, growth factors or serum) are seeded in each well of 24-well plates and allowed to settle for 1 hour. Next, 50 μL of the test compound is added followed by 50 μL of LPS (final concentration of 10 μg/mL). After 24h (37°C and 5% CO2) the supernatants and cell pellets are collected (1200 rpm, 5 min). THP-1 cell viability is tested using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT). MTT is dissolved at 2 mg/mL in PBS and aliquots are stored at -20°C. The MTT assay is performed according to the suppliers instructions. Absorbance of MTT converted into formazan is measured at a wavelength of 570 nm with background subtraction at 630 nm.

參考文獻(xiàn)：

1.Noedl H, et al. Antimicrob Agents Chemother. 2007 Feb;51(2):651-6.

溶解性：

DMSO:10 mM

保存條件：

2-8℃

配置溶液濃度參考：

	1mg	5mg	10mg
1 mM	1.361 ml	6.803 ml	13.606 ml
5 mM	0.272 ml	1.361 ml	2.721 ml
10 mM	0.136 ml	0.68 ml	1.361 ml
50 mM	0.027 ml	0.136 ml	0.272 ml

注意：

部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)

質(zhì)檢證書(COA)

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批號(hào)：JS298415 貨號(hào)：S20001-25g
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摩爾濃度計(jì)算器

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

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Azathramycin

9-Deoxo-9a-aza-9a-homo Erythromycin A (Desmethyl Azithromycin)