98. [IF=8.3] Huan Pu et al."Ultrasound-Responsive Nanobubbles for Breast Cancer: Synergistic Sonodynamic, Chemotherapy, and Immune Activation through the cGAS-STING Pathway."ACS Applied Materials & Interfaces.2025;17(13):19317–19334 97. [IF=8.7] Liying Xiao et al."Targeting drug cocktail hydrogel platform for inhibiting tumor growth and metastasis."Materials Today Bio.2025 Jun;32:101798 96. [IF=3.8] Xiu-mei Luan et al."Improvement of polarity-based solvent system for countercurrent chromatography in the guidance of solvent selectivity: n-hexane/ethyl acetate/ alcohol solvents/water as an example."JOURNAL OF CHROMATOGRAPHY A.2024 Nov;1736:465389 95. [IF=5.5] Hongji Pu et al."Antiproliferative agent attenuates post-thrombotic vein wall remodeling in murine and human subjects."JOURNAL OF THROMBOSIS AND HAEMOSTASIS.2024 Sep;: 94. [IF=4.4] Qu Minmin et al."Assessing genotoxic effects of chemotherapy agents by a robust in vitro assay based on mass spectrometric quantification of γ-H2AX in HepG2 cells."Frontiers in Pharmacology.2024 Jun;15: 93. [IF=2.1] Meng Zhaoyang et al."Study on Cytochrome P450 Metabolic Profile of Paclitaxel on Rats using QTOF-MS."CURRENT DRUG METABOLISM. 92. [IF=4.2] Pengxia Gao et al."Sensitive Detection of Genotoxic Substances in Complex Food Matrices by Multiparametric High-Content Analysis."MOLECULES.2024 Jan;29(14):3257 91. [IF=5.1] Danli Cao et al."Cannabidiol Inhibits Epithelial Ovarian Cancer: Role of Gut Microbiome."JOURNAL OF NATURAL PRODUCTS".2024;XXXX(XXX):XXX-XXX 90. [IF=4.6] Liying Xiao et al."Silk Nanofiber Carriers for both Hydrophilic and Hydrophobic Drugs to Achieve Improved Combination Chemotherapy."MACROMOLECULAR BIOSCIENCE.2024 Jan;:2300523 89. [IF=4.6] Liying Xiao et al."Silk Nanofiber Carriers for both Hydrophilic and Hydrophobic Drugs to Achieve Improved Combination Chemotherapy."MACROMOLECULAR BIOSCIENCE.2024 Jan;:2300523 88. [IF=4.5] Zirui Zhao et al."Transcriptomics and Physiological Analyses Reveal Changes in Paclitaxel Production and Physiological Properties in Taxus cuspidata Suspension Cells in Response to Elicitors."Plants-Basel.2023 Jan;12(22):3817 87. [IF=5] Haizhu Xing et al."Thymoquinone Alleviates Paclitaxel-Induced Peripheral Neuropathy through Regulation of the TLR4-MyD88 Inflammatory Pathway."ACS Chemical Neuroscience.2023;XXXX(XXX):XXX-XXX 86. [IF=4.6] Han Tao et al."Development of an invasion score based on metastasis-related pathway activity profiles for identifying invasive molecular subtypes of lung adenocarcinoma."Scientific Reports.2024 Jan;14(1):1-16 85. [IF=1.7] Na-Na He et al."Semisynthesis and in Vitro Anti-cancer Effect of New Magnolol Derivatives on the Cell Proliferation, Apoptosis, Migration, and Invasion of Human Hepatocellular Carcinoma SMMC-7721 Cells."CHEMICAL & PHARMACEUTICAL BULLETIN.2023 Nov;71(11):79 84. [IF=4.6] Zirui Zhao et al."Parameter Optimization of Ultrasonic–Microwave Synergistic Extraction of Taxanes from Taxus cuspidata Needles."MOLECULES.2023 Jan;28(23):7746 83. [IF=5.2] Zhe Wang et al."Fermentation of Betaphycus gelatinum Using Lactobacillus brevis: Growth of Probiotics, Total Polyphenol Content, Polyphenol Profile, and Antioxidant Capacity."Foods.10.3390/foods12183334 82. [IF=6.1] Shuxin Tang et al."Hypoglycemic effect of Lactobacillus plantarum-fermented mulberry pomace extract in vitro and in Caenorhabditis elegans."Food & Function.10.1039/D3FO02386A 81. [IF=2] Xinrui Wang et al."Rapid Characterization of Male and Female Taxus chinensis by Near-Infrared (NIR) Spectroscopy and High-Performance Liquid Chromatography (HPLC) with Orthogonal Partial Least Squares—Discriminant Analysis (OPLS-DA)."ANALYTICAL LETTERS. 80. [IF=5.1] Hongyan Lin et al."Modified Podophyllotoxin Phenoxyacetamide Phenylacetate Derivatives: Tubulin/AKT1 Dual-Targeting and Potential Anticancer Agents for Human NSCLC."JOURNAL OF NATURAL PRODUCTS.2023;XXXX(XXX):XXX-XXX 79. [IF=7.9] Jiangna Yan et al."Blocking LTB4 Signaling-mediated TAMs Recruitment by Rhizoma Coptidis Sensitizes Lung Cancer to Immunotherapy."PHYTOMEDICINE.2023 Jul;:154968 78. [IF=8] Yue Zhang et al."Co-Delivery Nanomicelles for Potentiating TNBC Immunotherapy by Synergetically Reshaping CAFs-Mediated Tumor Stroma and Reprogramming Immunosuppressive Microenvironment."International Journal of Nanomedicine. 77. [IF=8] Wenli Dang et al."Subcellular Organelle-Targeted Nanostructured Lipid Carriers for the Treatment of Metastatic Breast Cancer."International Journal of Nanomedicine. 76. [IF=11.504] Yunxiang Ma et al."Construction of butyric acid modified porous starch for stabilizing pickering emulsions: Encapsulation of paclitaxel."FOOD HYDROCOLLOIDS.2023 Sep;142:108858 75. [IF=4.927] Wengang Zhang et al."Polyphenol Profile and In Vitro Antioxidant and Enzyme Inhibitory Activities of Different Solvent Extracts of Highland Barley Bran."MOLECULES.2023 Jan;28(4):1665 74. [IF=5.561] Xiaomei Fu et al."Multi-Index Comprehensive Assessment Optimized Critical Flavonoids Extraction from Semen Hoveniae and Their In Vitro Digestive Behavior Evaluation."Foods.2023 Jan;12(4):773 73. [IF=6.819] Xiaoyan Xu et al."Application of mPEG-CS-cRGD/Bmi-1RNAi-PTX nanoparticles in suppression of laryngeal cancer by targeting cancer stem cells."DRUG DELIVERY.2023;30(1):Article: 2180112 72. [IF=5.135] Bushra et al."Microtubule cytoskeleton inhibition induced by taxol and vinorelbine affects encystation, proliferation, morphology, and gene expression of Cryptocaryon irritans protomont."AQUACULTURE.2023 Mar;567:739278 71. [IF=3.344] Yajing Zhang et al."Purification of Two Taxanes from Taxus cuspidata by Preparative High-Performance Liquid Chromatography."Separations.2022 Dec;9(12):446 70. [IF=3.344] Yajing Zhang et al."Separation and Purification of Taxanes from Crude Taxus cuspidata Extract by Antisolvent Recrystallization Method."Separations.2022 Oct;9(10):304 69. [IF=4.927] Cheng-Zhu Wu et al."Isobavachalcone Induces Multiple Cell Death in Human Triple-Negative Breast Cancer MDA-MB-231 Cells."MOLECULES.2022 Jan;27(20):6787 68. [IF=6.78] Qingqing Chen et al."Novel shikonin derivatives suppress cell proliferation, migration and induce apoptosis in human triple-negative breast cancer cells via regulating PDK1/PDHC axis."LIFE SCIENCES.2022 Dec;310:121077 67. [IF=4.136] Taiwei Wang et al."Gomisin A enhances the antitumor effect of paclitaxel by suppressing oxidative stress in ovarian cancer."ONCOLOGY REPORTS.2022 Nov;48(5):1-14 66. [IF=6.819] Xiaoming Cui et al."A novel ligand-modified nanocomposite microparticles improved efficiency of quercetin and paclitaxel delivery in the non-small cell lung cancer."DRUG DELIVERY 65. [IF=10.383] Weicai Wang et al."Drug-Induced Self-Assembly Cascade Nanoreactor for Synergistic Tumor Therapy."ACS Applied Materials & Interfaces.2022;14(39):44029–44038 64. [IF=3.204] Zhong-Bo Zhou et al."Bioactive polycyclic polyprenylated acylphloroglucinols from Hypericum scabrum."FITOTERAPIA.2022 Sep;161:105249 63. [IF=3.344] Yajing Zhang et al."Ultrasonic Extraction and Separation of Taxanes from Taxus cuspidata Optimized by Response Surface Methodology."Separations.2022 Aug;9(8):193 62. [IF=5.373] Haixu Zhou et al."A c-MWCNTs/AuNPs-based electrochemical cytosensor to evaluate the anticancer activity of pinoresinol from Cinnamomum camphora against HeLa cells."Bioelectrochemistry. 2022 Aug;146:108133 61. [IF=4.412] Zirui Zhao et al."Identification and Optimization of a Novel Taxanes Extraction Process from Taxus cuspidata Needles by High-Intensity Pulsed Electric Field."MOLECULES. 2022 Jan;27(9):3010 60. [IF=4.749] Liying Xiao et al."Silk Nanocarrier Size Optimization for Enhanced Tumor Cell Penetration and Cytotoxicity In Vitro."Acs Biomater Sci Eng. 2021;XXXX(XXX):XXX-XXX 59. [IF=1.779] Xin Hua et al."Combination of oridonin and TRAIL induces apoptosis in uveal melanoma cells by upregulating DR5."Int J Ophthalmol-Chi. 2021; 14(12): 1834–1842 58. [IF=6.4] Jia-Xin Cai et al."Hybrid Cell Membrane-Functionalized Biomimetic Nanoparticles for Targeted Therapy of Osteosarcoma."Int J Nanomed. 2022; 17: 837–854 57. [IF=4.36] Rumeng Wu et al."Preparation of the sphingolipid fraction from mycelia of Cordyceps sinensis and its immunosuppressive activity."J Ethnopharmacol. 2022 Jun;291:115126 56. [IF=1.679] Zhong-Bo Zhou et al."Two new polycyclic polyprenylated acylphloroglucinols from Hypericum curvisepalum N. Robson."Phytochem Lett. 2022 Apr;48:43 55. [IF=6.4] Juan Du et al."Two-Pronged Anti-Tumor Therapy by a New Polymer-Paclitaxel Conjugate Micelle with an Anti-Multidrug Resistance Effect."Int J Nanomed. 2022; 17: 1323–1341 54. [IF=2.276] Shu Jie et al."BTBD7 Downregulates E-Cadherin and Promotes Epithelial-Mesenchymal Transition in Lung Cancer."Biomed Res Int. 2019;2019:5937635 53. [IF=2.441] Ha Yinuer et al."Herb–Drug Interaction Potential of Licorice Extract and Paclitaxel: A Pharmacokinetic?Study in Rats."Eur J Drug Metab Ph. 2020 Apr;45(2):257-264 52. [IF=2.928] Shulei Gong et al."RFC3 induces epithelial?mesenchymal transition in lung adenocarcinoma cells through the Wnt/β?catenin pathway and possesses prognostic value in lung adenocarcinoma."Int J Mol Med. 2019 Dec;44(6):2276-2288 51. [IF=4.411] Xiao-Long Sun et al."Semi-Synthesis and In Vitro Anti-Cancer Evaluation of Magnolol Derivatives."Molecules. 2021 Jan;26(14):4302 50. [IF=4.411] Mengxia Wei et al."Ultrasound-Assisted Extraction of Taxifolin, Diosmin, and Quercetin from Abies nephrolepis (Trautv.) Maxim: Kinetic and Thermodynamic Characteristics."Molecules. 2020 Jan;25(6):1401 49. [IF=4.759] Fan Zhang et al."Ligand fishing via a monolithic column coated with white blood cell membranes: a useful technique for screening active compounds in Astractylodes lancea."J Chromatogr A. 2021 Sep;:462544 48. [IF=4.845] Li-shang Dai et al."1H NMR-based metabonomic evaluation of the pesticides camptothecin and matrine against larvae of Spodoptera litura."Pest Manag Sci. 2021 Jan;77(1):208-216 47. [IF=5.076] Liuli Xv et al."Structural Modification of Nanomicelles through Phosphatidylcholine: The Enhanced Drug-Loading Capacity and Anticancer Activity of Celecoxib-Casein Nanoparticles for the Intravenous Delivery of Celecoxib."Nanomaterials-Basel. 2020 Mar;10(3 46. [IF=5.091] Liting Guo et al."Preclinical Assessment of Paclitaxel- and Trastuzumab-Delivering Magnetic Nanoparticles Fe3O4 for Treatment and Imaging of HER2-Positive Breast Cancer."Front Med-Lausanne. 2021; 8: 738775 45. [IF=5.682] Chao Huang et al."Systems pharmacology dissection of Epimedium targeting tumor microenvironment to enhance cytotoxic T lymphocyte responses in lung cancer."Aging-Us. 2021 Jan 31; 13(2): 2912–2940 44. [IF=6.126] Weiyi Zhang et al."Cinnamaldehyde Enhances Antimelanoma Activity through Covalently Binding ENO1 and Exhibits a Promoting Effect with Dacarbazine."Cancers. 2020 Feb;12(2):311 43. [IF=6.15] Zhang Bing-bing et al."Lipid/PAA-coated mesoporous silica nanoparticles for dual-pH-responsive codelivery of arsenic trioxide/paclitaxel against breast cancer cells."Acta Pharmacol Sin. 2021 Apr;42(5):832-842 42. [IF=6.321] Zhe Ma et al."Enhanced Anticancer Efficacy of Dual Drug-Loaded Self-Assembled Nanostructured Lipid Carriers Mediated by pH-Responsive Folic Acid and Human-Derived Cell Penetrating Peptide dNP2."Pharmaceutics. 2021 May;13(5):600 41. [IF=6.419] Chunpeng He et al."Microfluidic-based fabrication and characterization of drug-loaded PLGA magnetic microspheres with tunable shell thickness."Drug Deliv. 2021;28(1):692-699 40. [IF=6.529] Yue Xiao et al."Predicting the herbal medicine triggering innate anti-tumor immunity from a system pharmacology perspective."Biomed Pharmacother. 2021 Nov;143:112105 39. [IF=6.843] Wenyuan Wang et al."Melanin-loaded biocompatible photosensitive nanoparticles for controlled drug release in combined photothermal-chemotherapy guided by photoacoustic/ultrasound dual-modality imaging."Biomater Sci-Uk. 2019 Sep;7(10):4060-4074 38. [IF=7.328] Yonghong Wang et al."Targeted delivery of quercetin by nanoparticles based on chitosan sensitizing paclitaxel-resistant lung cancer cells to paclitaxel."Mat Sci Eng C-Mater. 2021 Feb;119:111442 37. [IF=7.79] Shuangyu Liu et al."Paclitaxel-loaded magnetic nanocrystals for tumor neovascular-targeted theranostics: an amplifying synergistic therapy combining magnetic hyperthermia with chemotherapy."Nanoscale. 2021 Feb;13(6):3613-3626 36. [IF=8.198] Xiaowei Li et al."Biocatalysis of MnO2-Mediated Nanosystem for Enhanced Multimodal Therapy and Real-Time Tracking."Acs Sustain Chem Eng. 2020;8(35):13206–13214 35. [IF=13.273] Yuchu He et al."Tumor hypoxia relief overcomes multidrug resistance and immune inhibition for self-enhanced photodynamic therapy."Chem Eng J. 2019 Nov;375:122079 34. [IF=1.902] Zhangxiao Peng et al."Study on the pharmacokinetics and metabolism of costunolide and dehydrocostus lactone in rats by HPLC-UV and UPLC-Q-TOF/MS."Biomed Chromatogr. 2014 Oct;28(10):1325-1334 33. [IF=1.902] Zhang-xiao Peng et al."A platform for fast screening potential anti-breast cancer compounds in traditional Chinese medicines."Biomed Chromatogr. 2013 Dec;27(12):1759-1766 32. [IF=4.142] Shen Haibo et al."A high-throughput QCM chip configuration for the study of living cells and cell-drug interactions."Anal Bioanal Chem. 2017 Nov;409(27):6463-6473 31. [IF=4.29] Peng Zhang-xiao et al."Metabolic transformation of breast cancer in a MCF-7 xenograft mouse model and inhibitory effect of volatile oil from Saussurea lappa Decne treatment."Metabolomics. 2015 Jun;11(3):636-656 30. [IF=4.411] Li Yang et al."Seasonal Dynamics of Metabolites in Needles of Taxus wallichiana var. mairei."Molecules. 2016 Oct;21(10):1403 29. [IF=6.4] Kang Liu et al."Paclitaxel and quercetin nanoparticles co-loaded in microspheres to prolong retention time for pulmonary drug delivery."Int J Nanomed. 2017; 12: 8239–8255 28. [IF=8.198] Yuchu He et al."Regulatory Mechanism of Localized Surface Plasmon Resonance Based on Gold Nanoparticles-Coated Paclitaxel Nanoliposomes and Their Antitumor Efficacy."Acs Sustain Chem Eng. 2018;6(10):13543–13550 27. [IF=8.947] Yuan Guo et al."A light-controllable specific drug delivery nanoplatform for targeted bimodal imaging-guided photothermal/chemo synergistic cancer therapy."Acta Biomater. 2018 Oct;80:308 26. [IF=8.947] Haoan Wu et al."Injectable magnetic supramolecular hydrogel with magnetocaloric liquid-conformal property prevents post-operative recurrence in a breast cancer model."Acta Biomater. 2018 Jul;74:302 25. [IF=9.229] Qing-Shan Liu et al."Novel Beta-Tubulin-Immobilized Nanoparticles Affinity Material for Screening β-Tubulin Inhibitors from a Complex Mixture."Acs Appl Mater Inter. 2017;9(7):5725–5732 24. Shen, H., Zhou, T. & Hu, J. A high-throughput QCM chip configuration for the study of living cells and cell-drug interactions. Anal Bioanal Chem 409, 6463–6473 (2017). https://doi.org/10.1007/s00216-017-0591-4 23. Li, Xiaowei, et al. "Biocatalysis of MnO2-Mediated Nanosystem for Enhanced Multimodal Therapy and Real-Time Tracking." ACS Sustainable Chemistry & Engineering 8.35 (2020): 13206-13214.https://doi.org/10.1021/acssuschemeng.0c02367 22. Shu, Jie, et al. "BTBD7 downregulates E-cadherin and promotes epithelial-mesenchymal transition in lung cancer." BioMed research international 2019 (2019).https://doi.org/10.1155/2019/5937635 21. Ma, Zhe, et al. "Dual drug-loaded nano-platform for targeted cancer therapy: toward clinical therapeutic efficacy of multifunctionality." Journal of nanobiotechnology 18.1 (2020): 1-24.https://doi.org/10.1186/s12951-020-00681-8 20. Peng, Zhang-xiao, et al. "Metabolic transformation of breast cancer in a MCF-7 xenograft mouse model and inhibitory effect of volatile oil from Saussurea lappa Decne treatment." Metabolomics 11.3 (2015): 636-656. 19. Liu K, Chen W, Yang T, et al. Paclitaxel and quercetin nanoparticles co-loaded in microspheres to prolong retention time for pulmonary drug delivery. Int J Nanomedicine. 2017;12:8239-8255. Published 2017 Nov 13. doi:10.2147/IJN.S147028 18. Xv L, Qian X, Wang Y, Yu C, Qin D, Zhang Y, Jin P, Du Q. Structural Modification of Nanomicelles through Phosphatidylcholine: The Enhanced Drug-Loading Capacity and Anticancer Activity of Celecoxib-Casein Nanoparticles for the Intravenous Delivery of Celec 17. LIU, Qing-Shan, et al. Novel Beta-Tubulin-Immobilized Nanoparticles Affinity Material for Screening β-Tubulin Inhibitors from a Complex Mixture. ACS applied materials & interfaces, 2017, 9.7: 5725-5732.https://doi.org/10.1021/acsami.6b13477 16. Wu, Haoan, et al. "Injectable magnetic supramolecular hydrogel with magnetocaloric liquid-conformal property prevents post-operative recurrence in a breast cancer model." Acta biomaterialia 74 (2018): 302-311.https://doi.org/10.1016/j.actbio.2018.04.052 15. Peng, Z.-x., Wang, Y., Gu, X., Wen, Y.-y. and Yan, C. (2013), A platform for fast screening potential anti-breast cancer compounds in traditional Chinese medicines. Biomed. Chromatogr., 27: 1759-1766. https://doi.org/10.1002/bmc.2990 14. 彭文,范長(zhǎng)玲,張浩.lncRNA GAS6-AS2靶向miR-125a-3p調(diào)控肺癌A549細(xì)胞紫杉醇敏感性[J].中國(guó)腫瘤生物治療雜志,2021,28(01):23-30. 13. 齊志文,周昊,陳虹霞,張昌偉,鄧濤,王成章.漆酚基BPAU-NH_2-Gal紫杉醇載藥膠束的pH響應(yīng)性及其體外性能[J].林產(chǎn)化學(xué)與工業(yè),2020,40(05):121-128. 12. 白雅竹, 鄭志忠, 陳清智,等. 非洲馬鈴果4種吲哚類生物堿的體外抗腫瘤效果[J]. 亞熱帶植物科學(xué), 2019(3). 11. 周怡梅, 金瑩, 吳磊,等. 綠原酸對(duì)紫杉醇致小鼠外周神經(jīng)痛的影響[J]. 湖北科技學(xué)院學(xué)報(bào)(醫(yī)學(xué)版), 2019, 033(003):P.188-191. 10. 李情, 姚微, 楊超,等. 紫杉醇對(duì)CHMm細(xì)胞G2/M期的阻滯及對(duì)周期相關(guān)因子的影響[J]. 中國(guó)獸醫(yī)科學(xué), 2013, 043(012):1306-1312. 9. 王永紅, 于洪麗, 秦夢(mèng),等. 紫杉醇/油酰殼聚糖納米粒的理化特性及肺急性毒性評(píng)價(jià)[J]. 中國(guó)藥學(xué)雜志, 2018, 053(017):1485-1491. 8. 劉建慧,馬生軍,馬留純,曹雪琴,梁朔,呂苗,王穎,王萬勇,羅建民.海南和四川不同生長(zhǎng)年限曼地亞紅豆杉3種紫杉烷類活性成分的比較研究[J].中醫(yī)藥信息,2017,34(06):9-13. 7. 寧慧, 莫微. 校正超濾法測(cè)定木香烴內(nèi)酯和去氫木香內(nèi)酯的大鼠血漿蛋白結(jié)合率[J]. 中國(guó)現(xiàn)代中藥, 2015, 017(004):321-325,330. 6. 蔣愛, 李國(guó)源, 王鑫,等. 星點(diǎn)設(shè)計(jì)-效應(yīng)面法優(yōu)化紫杉醇-白樺脂酸混合納米混懸劑[J]. 中草藥, 2019, 50(04):852-859. 5. 褚冰, 丁敏, 易瓊. 抗EGFR單克隆抗體偶聯(lián)載紫杉醇納米粒對(duì)胃癌腫瘤靶向性能力研究[J]. 貴州醫(yī)藥, 2016(6期):563-566. 4. 尹楊峰 蔣磊.千金藤素通過MAT2B調(diào)節(jié)MAPK信號(hào)通路對(duì)宮頸癌細(xì)胞增殖和凋亡的影響[J].中國(guó)醫(yī)藥生物技術(shù) 2020 15(02):183-189. 3. 王光杰 顧俊峰 肖昀. 代謝型谷氨酸受體5在周圍神經(jīng)痛大鼠脊髓和背根神經(jīng)節(jié)的表達(dá)[J]. 中華實(shí)用診斷與治療雜志 2019(11). 2. 馬生軍 劉建慧 馬留純 王穎 曹雪琴 羅建民.不同產(chǎn)地及生長(zhǎng)年限曼地亞紅豆杉中10-脫乙?；涂ㄍあ?、三尖杉寧堿、紫杉醇量的比較分析[J].中草藥 2017 48(23):4979-4985. 1. 李昆太 彭衛(wèi)福 周佳 等. 一株產(chǎn)紫杉醇的南方紅豆杉內(nèi)生菌的分離與鑒定[J]. 江西農(nóng)業(yè)大學(xué)學(xué)報(bào) 2013 035(001):184-188.