貨號(hào)	規(guī)格	價(jià)格	上海	北京	武漢	南京
B21424-20mg	分析標(biāo)準(zhǔn)品,HPLC≥99.5%	￥40.00 B21424-20mg ￥40.00 現(xiàn)貨	2447 >10	-	-	-
B21424-50mg	分析標(biāo)準(zhǔn)品,HPLC≥99.5%	￥60.00 B21424-50mg ￥60.00 現(xiàn)貨	1019 11 >10	3	5	3
B21424-100mg	分析標(biāo)準(zhǔn)品,HPLC≥99.5%	￥110.00 B21424-100mg ￥110.00 現(xiàn)貨	507 >10	-	-	-
B21424-1g	分析標(biāo)準(zhǔn)品,HPLC≥99.5%	￥950.00 B21424-1g ￥950.00 現(xiàn)貨	52 >10	-	-	-

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產(chǎn)品介紹

Nicotinamide 是維生素 B3 或煙酸的一種形式，可抑制 SIRT2 的體外活性，其 EC50 值為 2 μM。 Nicotinamide 可抑制 90% 的黑色素瘤細(xì)胞數(shù)量，并增加細(xì)胞內(nèi) NAD+、ATP、ROS 水平。Nicotinamide 抑制黑色素瘤小鼠的腫瘤生長(zhǎng)并提高生存率，可用于黑色素瘤等皮膚癌相關(guān)的研究。

熔點(diǎn)：	128-131?°C(lit.)
沸點(diǎn)：	150-160°C
外觀：	白色至類白色粉末
溶解性：	Souble in DMSO ,H2O
敏感性：	對(duì)光敏感
儲(chǔ)存條件：	2-8℃
注意：	部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(19篇)

19. [IF=9.4] Weiqi Liu et al."Heterogeneous interfaces in confined microdomains of glycyrrhizic acid for polymorphism selection: Mechanisms and applications."JOURNAL OF COLLOID AND INTERFACE SCIENCE.2025 Mar;682:1017 18. [IF=5.6] Rongrong Li et al."Establishment of a novel large-scale targeted metabolomics method based on NFSWI-DDA mode utilizing HRMS and TQ-MS."TALANTA.2025 Jan;:127566 17. [IF=14.3] Xinyi Lu et al."NAD+ Metabolism Reprogramming Drives SIRT1-Dependent Deacetylation Inducing PD-L1 Nuclear Localization in Cervical Cancer."Advanced Science.2025 Feb;:2412109 16. [IF=12.7] Wenyue Xie et al."Cascaded diffusion-driven self-reinforced adhesive hydrogels for hydrophobic tissue closure."COMPOSITES PART B-ENGINEERING.2025 Apr;:112580 15. [IF=8.2] Yulong Wei et al."New insight into molecular mechanisms of different polyphenols affecting Sirtuin 3 deacetylation activity."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES".2024 May;:132026

14. [IF=8.1] Zhaocheng Tang et al."In vitro digestion under simulated saliva, gastric and small intestinal conditions and fermentation of nicotinamide mononucleotide, and its effects on the gut microbiota."FOOD RESEARCH INTERNATIONAL.2023 Nov;:113779 13. [IF=5.4] Bo Zhang et al."Integration of single-nucleus RNA sequencing and network disturbance to elucidate crosstalk between multicomponent drugs and trigeminal ganglia cells in migraine."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;319:117286 12. [IF=3.6] Su Wu et al."Antidiabetic activity of eupafolin through peroxisome proliferator-activated receptor-gamma and PI3K/Akt signaling in Type 2 diabetic rats."JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY.2023 Aug;:e23463 11. [IF=4.7] Guo-Ying Chen et al."Rapid and sensitive detection of alkaline phosphatase and glucose oxidase activity through fluorescence and colorimetric dual-mode analysis based on CuO NPs@ZIF-8 mediated enzyme-cascade reactions."Nanoscale Advances.2023 Aug;: 10. [IF=5.2] Meijie Song et al."Enhanced Production of β-Nicotinamide Mononucleotide with Exogenous Nicotinamide Addition in Saccharomyces boulardii-YS01."Foods.2023 Jan;12(15):2897 9. [IF=8.025] Guangzhen Zhou et al."Transcriptome and targeted metabolomic integrated analysis reveals mechanisms of B vitamin accumulation in Areca catechu nut development."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2023 Jun;241:124570 8. [IF=8.025] Chongyang Zhu et al."A pH-sensitive hydrogel based on carboxymethylated konjac glucomannan crosslinked by sodium trimetaphosphate: Synthesis, characterization, swelling behavior and controlled drug release."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECUL 7. [IF=3.645] Aijin Shen et al."Chemical profiling of Qingfei Paidu Decoction by triplex off-line two-dimensional liquid chromatography coupled with quadrupole time-of-flight mass spectrometry."Journal Of Separation Science. 2022 Jan 09 6. [IF=3.534] Zhaoyang Zhang et al."Molecular Mechanisms Involved in Supersaturation of Emodin Ternary Solid Dispersions Based on Bonding Agents."J Pharm Sci-Us. 2022 Jan;: 5. [IF=2.044] Chen Guo-Ying et al."Immobilized Kallikrein Microreactor Based on Capillary Electrophoresis for Online Enzyme Kinetics Analysis and Inhibitor Screening."Chromatographia. 2021 Oct 11 4. [IF=6.953] Chongyang Zhu et al."A pH-sensitive semi-interpenetrating polymer network hydrogels constructed by konjac glucomannan and poly (γ-glutamic acid): Synthesis, characterization and swelling behavior."Int J Biol Macromol. 2021 Aug;185:229 3. 鄔燕紅,胡新成,項(xiàng)琪,陳穎之,貝煜.化妝品中煙酰胺透皮吸收的臨床評(píng)估[J].香料香精化妝品,2020(04):61-64. 2. 吳金平, 杜浩, 陳細(xì)華, et al. 煙酸對(duì)雜交鱘幼魚(yú)生長(zhǎng)性能,肌肉品質(zhì)和抗氧化功能的影響[J]. 中國(guó)水產(chǎn)科學(xué), 2020(4):406-413. 1. 鄔燕紅、胡新成、項(xiàng)琪、陳穎之、貝煜. 化妝品中煙酰胺透皮吸收的臨床評(píng)估[J]. 香料香精化妝品 2020 No.181(04):67-70.

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