貨號	規(guī)格	價(jià)格	上海	北京	武漢	南京	購買數(shù)量
B20146-20mg	分析標(biāo)準(zhǔn)品,HPLC≥98%	￥400.00 B20146-20mg ￥400.00 現(xiàn)貨	73 5 >10	1	1	3
B20146-100mg	分析標(biāo)準(zhǔn)品,HPLC≥98%	￥1080.00 B20146-100mg ￥1080.00 現(xiàn)貨	20 >10	-	-	-

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產(chǎn)品介紹

熔點(diǎn)：	225-235°C
沸點(diǎn)：	893.7°C at 760 mmHg
比旋光度：	(EtOH)+46
外觀：	白色粉末
儲存條件：	2-8℃
注意：	部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(51篇)

51. [IF=4.4] Zheng Liang et al."The AMPK–mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis."MEDIATORS OF INFLAMMATION.2024 Oct;2024(1):4777789 50. [IF=2.9] Menglin Wang et al."Saikosaponin A alleviates depressive-like behavior induced by reserpine in mice by regulating gut microflora and inflammatory responses."PLoS One.2025 Feb;20(2):e0311207 49. [IF=4] Dongbo Li et al."Integrated metabolomics and intestinal microbiota analysis to reveal anti-post-weaning diarrhea mechanisms of Modified Yupingfeng Granule in Rex rabbits."Frontiers in Microbiology.2025 Apr;16: 48. [IF=4.3] Zhang Wenli et al."Evaluation of different ecological regions for cultivation of best quality Bupleurum: a case study from Shanxi, China."BMC PLANT BIOLOGY.2025 Dec;25(1):1-14 47. [IF=4.4] Yingchao Wu et al."Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway."Frontiers in Pharmacology.2025 Apr;16:

46. [IF=4.8] Wei Li et al."Kaempferol modulates ɑ2M secretion in bone marrow-derived macrophages by downregulating GR/PER1-mediated lipid metabolism to attenuate the emotional stress-aggravated metastasis of prostate cancer."JOURNAL OF ETHNOPHARMACOLOGY.2025 Jan;339:1 45. [IF=4.1] Shengwei Zhou et al."Suitable concentrations of brassinolide application enhances growth performance and saikosaponin biosynthesis by transcriptional activation of triterpenoid pathway genes in Bupleurum chinense DC."Frontiers in Plant Science.2025 Mar;16 44. [IF=4.4] Nan Li et al."Wuling capsule alleviates hyperuricaemia and protects UA- injured HK-2 cells by regulating uric acid transporter proteins."Frontiers in Pharmacology.2025 Apr;16: 43. [IF=5.4] Ruolan Sun et al."Homotherapy-for-heteropathy of Bupleurum Chinense DC.-Scutellaria baicalensis Georgi in treating depression and colorectal cancer: A network pharmacology and animal model approach."JOURNAL OF ETHNOPHARMACOLOGY".2024 Mar;:118038 42. [IF=3.4] Jiaxin Yin et al."Comprehensive multicomponent characterization and quality assessment of Xiaoyao Wan by UPLC-Q-Orbitrap-MS, HS-SPME-GC-MS and HS-GC-IMS."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2024 Feb;239:115910 41. [IF=4.1] Liangliang He et al."A multi-module structure labelled molecular network orients the chemical profiles of traditional Chinese medicine prescriptions: Xiaoyao San, as an example."JOURNAL OF CHROMATOGRAPHY A.2024 Jan;1715:464613 40. [IF=5.4] Liangxin Zhao et al."UPLC-Q-Exactive/MS based analysis explore the correlation between components variations and anti-influenza virus effect of four quantified extracts of Chaihu Guizhi decoction."JOURNAL OF ETHNOPHARMACOLOGY.2023 Oct;:117318 39. [IF=2.6] Liu Xueqi et al."In Vivo Evaluation of Self-assembled nano-Saikosaponin-a for Epilepsy Treatment."MOLECULAR BIOTECHNOLOGY.2023 Aug;:1-11 38. [IF=4.6] Zhenhuan Wang et al."Quantitative and Differential Analysis between Bupleurum chinense DC. and Bupleurum scorzonerifolium Willd. Using HPLC-MS and GC-MS Coupled with Multivariate Statistical Analysis."MOLECULES.2023 Jan;28(15):5630 37. [IF=3.1] Tian Lan et al."Saikosaponin A triggers cell ferroptosis in hepatocellular carcinoma by inducing endoplasmic reticulum stress-stimulated ATF3 expression."BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.2023 Sep;674:10 36. [IF=5.4] Jie Tang et al."Study on the mechanism of Shuganzhi Tablet against nonalcoholic fatty liver disease and lipid regulation effects of its main substances in vitro."JOURNAL OF ETHNOPHARMACOLOGY.2023 Nov;316:116780 35. [IF=4.141] Yiqing Peng et al."Assessment of Genetic Diversity in Bupleurum spp. Basing Agronomic Traits, Medicinal Components and ISSR Markers."Genes.2023 Apr;14(4):951 34. [IF=6.656] Minna Huang et al."Saikosaponin A and D attenuate skeletal muscle atrophy in chronic kidney disease by reducing oxidative stress through activation of PI3K/AKT/Nrf2 pathway."PHYTOMEDICINE.2023 Jun;114:154766 33. [IF=3.369] Li Liu et al."Effects of Trichoderma harzianum biofertilizer on growth, yield, and quality of Bupleurum chinense."Plant Direct.2022 Nov;6(11):e461 32. [IF=9.756] Jiling Feng et al."Saikosaponin A enhances Docetaxel efficacy by selectively inducing death of dormant prostate cancer cells through excessive autophagy."CANCER LETTERS.2023 Feb;554:216011 31. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199 30. [IF=4.927] Linlin Yang et al."Drought Stress Stimulates the Terpenoid Backbone and Triterpenoid Biosynthesis Pathway to Promote the Synthesis of Saikosaponin in Bupleurum chinense DC. Roots."MOLECULES.2022 Jan;27(17):5470 29. [IF=2.977] An-rong Wang et al."Saikosaponin A improved depression-like behavior and inhibited hippocampal neuronal apoptosis after cerebral ischemia through p-CREB/BDNF pathway."Behav Brain Res. 2021 Apr;403:113138 28. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950 27. [IF=3.205] Jie Tang et al."Metabolite profiling of Shuganzhi tablets in rats and pharmacokinetics study of four bioactive compounds with liquid chromatography combined with electrospray ionization tandem mass spectrometry."J Chromatogr B. 2021 Aug;1179:122827 26. [IF=4.36] Xiaojing Zhang et al."A new discovery: Total Bupleurum saponin extracts can inhibit the proliferation and induce apoptosis of colon cancer cells by regulating the PI3K/Akt/mTOR pathway."J Ethnopharmacol. 2022 Jan;283:114742 25. [IF=4.534] Jikun Du et al."Saikosaponin-A induces apoptosis of cervical cancer through mitochondria- and endoplasmic reticulum stress-dependent pathway in vitro and in vivo: involvement of PI3K/AKT signaling pathway."Cell Cycle. 2021;20(21):2221-2232 24. [IF=5.81] Cui Lihua et al."Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway."Front Pharmacol. 2021 Jun;0:1369 23. [IF=3.205] Zhuangzhuang Li et al."Simultaneous quantification of fifteen compounds in rat plasma by LC-MS/MS and its application to a pharmacokinetic study of Chaihu-Guizhi decoction."J Chromatogr B. 2019 Jan;1105:15 22. [IF=3.216] Yu Hong et al."Saikosaponin A modulates remodeling of Kv4.2-mediated A-type voltage-gated potassium currents in rat chronic temporal lobe epilepsy."Drug Des Dev Ther. 2018; 12: 2945–2958 21. [IF=4.411] Dan-Dan Tian et al."Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats."Molecules. 2016 Jun;21(6):696 20. [IF=4.411] Wei Wang et al."In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism."Molecules. 2016 May;21(5):597 19. Wang, Wei, Dan-Dan Tian, and Zhang-Jin Zhang. "In Vitro Effects of Concomitant Use of Herbal Preparations on Cytochrome P450s Involved in Clozapine Metabolism."?Molecules?21.5 (2016): 597.https://doi.org/10.3390/molecules21050597 18. Tian D-D, Wang W, Wang H-N, Sze SCW, Zhang Z-J. Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats. Molecules. 2016; 21(6):696. https://doi.org/10.3390/molecules 17. 李壯壯, 張靜, 趙紹哲,等. 指紋圖譜與化學(xué)計(jì)量學(xué)結(jié)合優(yōu)選柴胡桂枝顆粒水提工藝[J]. 中成藥, 2018, v.40(08):199-203. 16. 黃湘陳豐連曹騁等. HPLC-ELSD全成分指紋圖譜研究疏肝理脾方配伍前后化學(xué)成分的變化[J]. 化學(xué)與生物工程 2020 037(001):59-64. 15. 楊夢玲, 尤朋濤, 何麗珊,等. 基于UPLC-MS/MS分析胃潰瘍模型大鼠口服加味小柴胡顆粒后血漿中8種有效成分的藥代動力學(xué)[J]. 中國中藥雜志, 2018, 43(18). 14. 趙昕彤, 辛國, 辛宇,等. 煎煮時(shí)間對柴胡中柴胡皂苷A和柴胡皂苷D含量的影響[J]. 人參研究, 2017. 13. 廖念, 龐雪, 周逸群,等. 正交試驗(yàn)法優(yōu)選北柴胡麩炒工藝[J]. 中國藥師, 2017, 020(004):738-740. 12. 潘龍,牛俊麗,卜登攀,杜洪,程建波,孫先枝,王秀敏,秦俊杰,袁耀明,張幸開.柴胡皂苷對體外發(fā)酵參數(shù)及細(xì)菌數(shù)量變化的影響[J].草業(yè)學(xué)報(bào),2015,24(06):85-91. 11. 朱雙龍,陳旭義,段會全,劉迎節(jié),孫中磊,徐云強(qiáng).柴胡皂苷a影響大鼠急性脊髓損傷后機(jī)體炎癥水平表達(dá)的實(shí)驗(yàn)研究[J].天津醫(yī)科大學(xué)學(xué)報(bào),2017,23(04):300-303. 10. 朱雙龍, 段會全, 劉英富,等. 柴胡皂苷a對大鼠急性脊髓損傷的神經(jīng)保護(hù)作用與機(jī)制研究[J]. 中國修復(fù)重建外科雜志, 2017, 031(007):825-829. 9. 胡冬蓉, 禤正正, 謝煒,等. 柴胡疏肝湯高效液相指紋圖譜的建立及含量測定[J]. 時(shí)珍國醫(yī)國藥, 2017(6):1310-1314. 8. 曹雪, 蔡廣知, 趙凌,等. 基于復(fù)合質(zhì)量常數(shù)的北柴胡飲片等級評價(jià)[J]. 中國實(shí)驗(yàn)方劑學(xué)雜志, 2018(18). 7. 李英, 焦倩, 張?zhí)焯?等. 基于地形因子的河北省北柴胡生態(tài)適宜性區(qū)劃研究[J]. 中國中藥雜志, 2017, 042(022):4402-4407. 6. 郭泰麟李丹丹張慧. 南北柴胡HPLC-ELSD指紋圖譜的研究[J]. 中國民族民間醫(yī)藥 2020 029(006):19-24. 5. 廖念龐雪周逸群等. 北柴胡麩煨工藝的正交試驗(yàn)法優(yōu)選[J]. 時(shí)珍國醫(yī)國藥 2017(05):96-98. 4. 龐雪廖念周逸群等. 不同炮制方法對北柴胡中柴胡皂苷含量的影響[J]. 時(shí)珍國醫(yī)國藥 2016(12):2906-2908. 3. 邱云蘇健龐雪等. 不同炮制方法對北柴胡中柴胡皂苷a、d的含量影響[J]. 湖南中醫(yī)藥大學(xué)學(xué)報(bào) 2016(2期):51-53. 2. 寧艷梅楊秀娟陳暉張金保楊韜任遠(yuǎn).不同比例鱉血炮制柴胡制品中柴胡總皂苷含量測定與比較[J].中獸醫(yī)醫(yī)藥雜志 2019 38(05):9-13. 1. 辛國趙昕彤李文等. 不同時(shí)間煎煮柴胡對五柴胡飲中柴胡皂苷含量及藥效學(xué)的影響[J]. 長春中醫(yī)藥大學(xué)學(xué)報(bào) 2018(4):641-644.

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柴胡皂苷A

Saikosaponin A